商鋪名稱：武漢菲恩生物科技有限公司
聯(lián)系人：王先生（先生）
聯(lián)系手機(jī)：
固定電話：
企業(yè)郵箱：3495998903@qq.com
聯(lián)系地址：武漢市江夏區(qū)高新大道818號(hào)高科醫(yī)療器械園B9棟
郵編：430206
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| 產(chǎn)品參數(shù) | |||
|---|---|---|---|
| 品牌 | 菲恩生物 | ||
| 適用范圍 | 僅供科研使用 | ||
| 規(guī)格 | 100μg | ||
| 加工定制 | 否 | ||
| 驗(yàn)證應(yīng)用 | ELISA | ||
| WB | |||
| IHC | |||
| IF | |||
| 宿主 | 小鼠 | ||
| 適應(yīng)種屬 | 人源，小鼠，大鼠 | ||
| 研究領(lǐng)域 | 新陳代謝 | ||
| 可售賣地 | 全國(guó) | ||
| 材質(zhì) | 液體 | ||
名稱：抗LONP1抗體(anti- LONP1 antibody)
貨號(hào)：FNab04821
適應(yīng)種屬：人源，小鼠，大鼠
規(guī)格：100ug(微克)
狀態(tài)：液體
純化方法：蛋白A/G柱純化
純度：經(jīng)sds-page分析,純度大于95
宿主：小鼠
亞型：IgG2a
存儲(chǔ)：用添加了0.02疊氮化鈉和50甘油的pbs溶解,ph值7.3,可在-20℃下保存12個(gè)月（避免反復(fù)凍融）
免疫原：lon peptidase 1, mitochondrial
免疫原別稱：PRSS15
分子量：100 kDa
驗(yàn)證應(yīng)用：ELISA, WB, IHC, IF
建議稀釋比例：WB: 1:500-1:10000; IHC: 1:400-1:1600; IF: 1:10-1:100
克隆性：?jiǎn)慰寺?/p>
uniprot id：P36776
背景介紹：ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein。
圖像：
Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab04821 (LONP1 Antibody) at dilution of 1:800 heat mediated antigen retrieved with Tris-EDTA buffer (pH9)。
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04821 (LONP1 Antibody) at dilution of 1:5000。
